A paradigm shift for the prevention and treatment of individual and global obesity


The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of the world, it continues to increase. Current recommendations for preventing and treating obesity are based mainly on the notion that overeating results from hedonic eating as a result of unlimited access to palatable foods, particularly those high in sugar and fat, and that hedonic centers are able to "override" the body's homeostatic mechanisms. 


Diabetes Metab Syndr Obes. 2018 Nov 29;11:855-861. doi: 10.2147/DMSO.S183777. eCollection 2018.


Slyper AH


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